Related Experiment Video
Updated: Aug 7, 2026

Murine Fetal Echocardiography
Published on: February 15, 2013
Imaging comparison of basic cardiac views between two- and three-dimensional ultrasound in normal fetuses in anterior
Po-Hui Wang1, Gin-Den Chen, Long-Yau Lin
1Department of Obstetrics and Gynecology, Chung Shan Medical and Dental College Hospital Taichung, Taiwan. obs@csh.org.tw
Objective:
When the fetal spine is in anterior position, it shadows the fetal heart, resulting in the difficult visualization using two-dimensional (2D) ultrasound. The purpose of this study was to compare the basic cardiac views of normal fetuses between 2D and 3D ultrasound to demonstrate whether 3D ultrasound improved the visualization of these views in fetuses in anterior spine positions. In addition, inter- and intra-observation reliabilities of basic cardiac views using 3D ultrasound were evaluated for their clinical applicability.
Methods:
Using a multiplanar technique, integrated 3D ultrasound was used to display the four-chamber view, aortic outflow tract and pulmonary outflow tract in fetuses in anterior spine positions for 23 uncomplicated singleton pregnant women. The imaging visualizations of these views for the 23 fetuses in 3D ultrasound were compared with those in 2D ultrasound using the McNemar test. We also evaluated the inter- and intra-observation differences of each basic cardiac view in 3D ultrasound using the kappa statistic and McNemar test, respectively.
Results:
Only in the pulmonary outflow tract, 3D ultrasound had significantly better visualization than the 2D ultrasound in the fetuses in anterior spine positions (p < 0.05). There was good inter-observation reliability and no intra-observation differences for the technique were observed.
Conclusions:
Among the basic cardiac views in fetuses in anterior spine positions, 3D ultrasound improved the visualization of pulmonary outflow and provided reliable alternate technique for clinical use.
Related Concept Videos
Imaging Studies for Cardiovascular System I:Echocardiography
Indications: Echocardiography is utilized to diagnose heart failure, valve disorders, and myocardial infarction. It also assesses cardiac structures' size, shape, and motion, evaluates...
Imaging Studies for Cardiovascular System II:Types of Echocardiography
Types of Echocardiography
Transthoracic Echocardiography (TTE)
TTE is the most common type of echocardiogram which involves placing a transducer on the patient's chest, emitting sound waves to create heart images. TTE is invaluable for evaluating the heart's size, structure, and motion, making it particularly useful for diagnosing...
Imaging Studies for Cardiovascular System V: CT

