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Single-lead VDD-pacing system incorporating high impedance stimulation: a multicentre study.
B Nowak1, C W Israel, D Gascon
1II Medical Clinic, University Mainz, Germany. nowak@ccb.de
Summary
This study shows a new VDD pacing system with a high impedance, single-pass lead offers reliable atrial sensing and stable stimulation. The system performed well in patients with high-degree atrioventricular block over three months.
Area of Science:
- Cardiology
- Biomedical Engineering
- Medical Devices
Background:
- High-degree atrioventricular (AV) block necessitates pacing solutions.
- VDD pacing systems require reliable atrial sensing and stable ventricular stimulation.
- Advancements in lead technology aim to improve pacing system performance and longevity.
Purpose of the Study:
- To evaluate the performance of a novel VDD pacing system.
- To assess a new high impedance, single-pass VDD lead with a bipolar, steroid-eluting design and full-ring atrial dipole.
Main Methods:
- Implantation of the new VDD pacing system in 46 patients with high-degree AV block.
- Follow-up assessments at pre-discharge, 6 weeks, and 3 months.
- Evaluation of P-wave amplitude, atrial sensing reliability, AV-synchronous stimulation, lead impedance, ventricular pacing thresholds, and R-wave amplitude.
Main Results:
- Stable P-wave amplitude (1.18–1.43 mV) and reliable atrial sensing.
- High AV-synchronous stimulation rates (98.79%–99.73% at rest, 99.57% on Holter).
- Stable high lead impedance (1000–1167 Ω) and consistent ventricular pacing thresholds (0.47–0.74 V). R-wave amplitude remained stable (14.9–16.7 mV).
Conclusions:
- The new single-pass VDD lead system demonstrated reliable performance.
- The system provided dependable atrial sensing and stable high impedance stimulation.
- The VDD pacing system proved effective over a 3-month follow-up period.