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Chronological change of brain abscess in (1)H magnetic resonance spectroscopy
H Akutsu1, A Matsumura, T Isobe
1Department of Neurosurgery, Institute of Clinical Medicine, University of Tsukuba, Tennodai 1-1-1,Tsukuba, Ibaraki 305-8575, Japan.
Abstract:
We studied chronological magnetic resonance spectral changes in brain abscesses before and after medical and/or surgical treatment. We examined five patients with MRI imaging and (1)H magnetic resonance spectroscopy (MRS) on two or more occasions, using two volume-of-interest patterns, and saw chronological changes related to the evolution of the abscess. A spectrum specific for brain abscess was found in three of the five cases, while two showed a single lactate peak in the first study. In two cases, phenylalanine or alanine appeared in the second study. We observed the disappearance of the specific spectra and a single lactate peak following surgery. Only one patient showed different spectra in different volume of interest.