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Anticholinergic poisoning from a large dose of Scopolia extract
Sheng-Wen Cheng1, Wei-Hsiung Hu, Dong-Zong Hung
1Department of Emergency Medicine, Taichung Veterans General Hospital, Chung-Sun Medical and Dental College, Taiwan.
Veterinary and Human Toxicology
|July 26, 2002
Abstract:
Scopolia extract (SE) contains hyoscyamine and scopolamine, which are both anticholinergic. It is usually used as a patent medicine to treat gastrointestinal disorders, to relieve spasmotic discomfort, or to decrease the secretion of gastric acid. Poisoning by SE presents similar symptoms and signs as other types of anticholinergic poisoning. We report a case of severe anticholinergic poisoning after accidentally drinking 8 ml of SE. The patient presented with acute delirium and was successfully treated with physostigmine.