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Primary bilateral parenchymal renal Aspergillus infection
Scott W Lisson1, Walter C Hellinger, Raul O Parra
1Department of Urology, Mayo Clinic Jacksonville, Jacksonville, Florida 32224, USA.
Abstract:
Isolated renal fungal infection is rare. Most patients with either an opportunistic or primary fungal infection have an altered immune status. Common predisposing factors include malignancy, corticosteroid use, diabetes, and iatrogenic or infective immunosuppression. We report a previously healthy patient with bilateral, recurrent renal Aspergillus infection requiring left total and right partial nephrectomies to adequately manage his disease process.
Insights
Isolated renal fungal infections are rare, often affecting immunocompromised individuals. This case highlights a previously healthy patient experiencing recurrent Aspergillus kidney infections, necessitating surgical intervention.
Area of Science:
- Nephrology
- Mycology
- Infectious Diseases
Background:
- Renal fungal infections are uncommon, typically occurring in patients with compromised immune systems.
- Predisposing factors include malignancy, corticosteroid use, diabetes, and immunosuppression.
- Aspergillus species are a common cause of fungal infections.
Observation:
- A previously healthy individual presented with bilateral, recurrent renal Aspergillus infection.
- The patient had no identifiable risk factors for immunosuppression.
Findings:
- The recurrent nature of the infection in an otherwise healthy host was unusual.
- Surgical management, including nephrectomies, was required to control the infection.
Implications:
- This case expands the understanding of renal fungal infections beyond typical immunocompromised populations.
- Highlights the importance of considering fungal etiologies in complex or recurrent renal infections.
- Suggests potential for novel diagnostic or therapeutic approaches in rare renal mycoses.