Related Experiment Video
Updated: Sep 30, 2026

Induction and Phenotyping of Acute Right Heart Failure in a Large Animal Model of Chronic Thromboembolic Pulmonary Hypertension
Published on: March 17, 2022
Severe ARDS may cause right heart failure with extreme hepatomegaly but without hepatic failure
E Søreide1, S Harboe, K Søndenaa
1Department of Anaesthesia, Rogaland Central and University Hospital, Stavanger, Norway. soed@sir.no
Abstract:
A young trauma patient developed severe adult respiratory distress syndrome (ARDS), right heart failure, hepatic congestion and an extreme hepatomegaly but no hepatic failure. The patient needed 100% oxygen during ventilatory support for 80 days and was weaned from the ventilator after more than 100 days. The hepatomegaly gradually disappeared. Four months after the injury, the anatomical shape of the lungs, heart and liver were normalized. This case illustrates that severe ARDS may cause right heart failure and extreme hepatomegaly due to venous congestion in the liver and spleen, but without hepatic failure.
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