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Pitfalls in diagnosis of early stage malignant peritoneal mesothelioma: a case report
Paul S F Lee1, K M Auyeung, D Ann King
1Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, Shatin, Hong Kong, China. leesfp@hotmail.com
Abstract:
Malignant peritoneal mesothelioma (MPM) is a rare condition with an overall incidence of one to two cases per million [Arch. Surg. 123 (1988) 765.]. It is a tumour that arises from the mesothelium of a serosal cavity. While simultaneous peritoneal and pleural involvement is found in 30-45% of cases of mesothelioma, solitary peritoneal involvement is found only in 10-20%. The disease usually presents late. As a result, most reported cases in the radiological literature describe features of the advanced disease only. We report the radiological findings in early stage of MPM in a patient who was successfully treated by surgery. The diagnostic pitfalls in early stage disease are discussed and the radiological literature of MPM is reviewed.
Insights
Malignant peritoneal mesothelioma (MPM) is a rare cancer. This study highlights early-stage radiological findings and diagnostic challenges in MPM, aiding timely surgical treatment.
Area of Science:
- Oncology
- Radiology
- Pathology
Background:
- Malignant peritoneal mesothelioma (MPM) is a rare neoplasm originating from the mesothelium of serosal cavities.
- While often presenting with simultaneous pleural involvement, solitary peritoneal disease is less common.
- MPM typically exhibits late-stage presentation, limiting radiological data on early disease manifestations.
Observation:
- This report details the radiological findings in an early-stage MPM case.
- The patient underwent successful surgical treatment.
- Diagnostic challenges associated with early-stage MPM are discussed.
Findings:
- Radiological features of early-stage MPM can be subtle and pose diagnostic challenges.
- Timely diagnosis is crucial for effective surgical intervention.
- Review of radiological literature on MPM is presented.
Implications:
- Enhanced understanding of early-stage MPM radiological findings can improve diagnostic accuracy.
- Early detection and surgical treatment offer improved patient outcomes.
- This case study contributes valuable insights for radiologists and oncologists managing MPM.
