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Related Experiment Videos

Liberation from prolonged mechanical ventilation.

David J Scheinhorn1, David C Chao, Meg Stearn-Hassenpflug

  • 1Barlow Respiratory Research Center, 2000 Stadium Way, Los Angeles, CA 90026, USA. djs@barlow2000.org

Critical Care Clinics
|July 27, 2002
PubMed
Summary
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Patients weaned from prolonged mechanical ventilation (PMV) require extensive rehabilitation. While many patients achieve functional independence and a satisfactory quality of life, long-term survival rates vary significantly based on age and premorbid condition.

Area of Science:

  • Critical Care Medicine
  • Pulmonology
  • Rehabilitation Medicine

Background:

  • Patients undergoing prolonged mechanical ventilation (PMV) often face extended recovery periods post-weaning.
  • Success rates for restorative care after PMV are highly specific to institutions and patient populations.
  • Comparing outcomes is challenging due to varying patient acuity and selection factors.

Purpose of the Study:

  • To analyze discharge disposition, survival rates, and quality of life (QOL) in patients after PMV.
  • To identify factors influencing outcomes, such as age and premorbid functional status.
  • To assess the effectiveness of multidisciplinary rehabilitation and discharge planning.

Main Methods:

  • Review of institutional and published data on patients weaned from mechanical ventilation.

Related Experiment Videos

  • Analysis of discharge home rates, 1-year survival, and functional independence.
  • Inclusion of QOL and functional status measures using validated instruments where available.

    • Main Results:

    • Discharge to home rates vary widely (20-57%), with higher rates in younger, postsurgical patients.
    • 1-year survival rates are generally around 50%, with significantly better outcomes for younger, more independent patients.
    • Functional independence at 1 year post-discharge is achieved by a minority of survivors (8-11.5%), with QOL often influenced by underlying chronic conditions.

    Conclusions:

    • Weaning from PMV is a safe and often successful critical care activity, but long-term outcomes require careful assessment.
    • Multidisciplinary rehabilitation and discharge planning are crucial for improving patient outcomes.
    • Further multicenter studies are needed to establish benchmarks for weaning, disposition, and survival, and to fully understand QOL and functionality in this complex patient group.