[Application of platelet-rich plasma in oral surgery. Theoretical background and practical requirements--review]

At the Department of Oral Surgery and Dentistry of Semmelweis University different studies have been carried out on the ossification, the use of various bone-substitutes and methods of bone augmentation. The aim of the present paper is to overview the literature background of an autogenous blood preparation (platelet rich plasma) with osteoinductive mechanisms applied in combination with osteoconductive bone substitutes. The role of platelet rich plasma is described in the mechanism of bone substitution, outlining the advantages of its application and the theoretical as well as the practical background of its clinical use. The routine use of platelet rich plasma has became very popular in a relatively short period of time in oral surgery though even today research and development are still very intensive in this field. According to many publications the use of autogenous blood preparations is an effective adjunctive method applied in bone substitutive therapies.