Related Experiment Video
Updated: Sep 30, 2026
Intracameral Injection in Rats with Low Risk of Adverse Effects
Published on: May 31, 2024
Antibiotic prophylaxis in rhinosurgery
Florian Bandhauer1, Daniela Buhl, Rudolf Grossenbacher
1Department of Otorhinolaryngology-Head and Neck Surgery, University Hospital, Zurich, Switzerland.
Background:
This study investigated the in vivo efficacy of nasal packing containing an antibiotic substance after septal and turbinate surgery on the potentially infectious nasal flora (Staphylococcus aureus, etc.) without systemic administration of antibiotics.
Methods:
The study was designed as an exploratory randomized trial. Three types of packings were used on 110 patients because of septoplasty and/or turbinate surgery. Packings were distributed randomly among three groups. The first and second groups received an antibiotic-free sample (polyvinyl acetate sponge and cotton gauze strips with sea-salt ointment) and the third group received an antibiotic one (cotton gauze strips with polymyxin-B-sulfate and oxytetracycline ointment). The nasal flora was determined by microscopy and cultures, both preoperatively and after elimination of the packing.
Results:
Significantly less growth of the potentially infectious nasalflora overall and of S. aureus in particular was found in the group with the antibiotic packing.
Conclusion:
Antibiotic-containing nasal packing effectively inhibits potentially infectious germs (including S. aureus) in the nasal flora and secondarily may diminish the incidence of postoperative infections.
Related Concept Videos
01:30Epistaxis
Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
01:29Suctioning the Nasopharyngeal Airway
Equipment Required
01:26Tonsillitis II: Management
01:25Clinical Significance of Antibiotic Resistance
01:25Transmission-based Precautions II: Airborne and Protective Environment
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
01:23Chronic Pharyngitis
Etiology
It often arises from persistent viral or bacterial infections affecting sinuses and tonsils.
Additional contributing factors include inadequate dental hygiene, mouth breathing, recurring tonsillitis, allergic rhinitis, laryngopharyngeal reflux, and exposure to smoke, chemicals, and other environmental pollutants. Allergic reactions to pollen, mold, and pet dander, chronic cough, excessive voice usage,...