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Intratumoral fat in neurofibroma
Sung Ku Ahn1, Hyung Jin Ahn, Tae-Hyun Kim
1Department of Dermatology, Yonsei University Wonju College of Medicine, Wonju, Korea. ahnsk@wonju.yonsei.ac.kr
The American Journal of Dermatopathology
|July 27, 2002
Abstract:
Three cases of a solitary neurofibroma showing focal fatty changes are reported. Fatty changes in a neurofibroma are rarely observed and have not been reported, and also, the pathogenesis of neurofibroma has not been clarified. We postulate that the fatty changes in a neurofibroma may be the result of so-called senescent change or chronic injury. The origin of adipose cells may be attributable to fatty infiltration from abutting tissues or to a metaplasia of tumor cells or resident fibroblasts.