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Updated: Jul 20, 2026

Method of Studying Palatal Fusion using Static Organ Culture
Published on: September 19, 2015
Sleep-related obstructive disordered breathing in cleft palate patients after palatoplasty
Edmund Rose1, Richard Staats, Ulrike Thissen
1Department of Orthodontics, School of Dental Medicine, Robert Koch Clinic, Medical School, University of Freiburg, Germany. rose@zmk2.ukl.uni-freiburg.de
Abstract:
Sleep-disordered breathing is frequently associated with children presenting congenital midface defects. Because of structural and functional anomalies in the upper airway, children with cleft palate, especially after surgery, may carry a higher risk of developing sleep-disordered breathing. However, the presence of such sleep-disordered breathing in older cleft palate children has not been emphasized. The aim of this comparative overnight cardiorespiratory sleep study was to evaluate cleft palate patients according to sleep-disordered breathing. A group of 43 cleft palate children (17 girls and 26 boys; mean age, 12.1 +/- 3.8 years) was compared with a control group of 20 randomly selected, noncleft children matched for age, sex, and body mass index. None of the patients suffered from manifest sleep-disordered breathing. Cleft palate patients had a statistically significantly higher respiratory disturbance index and snoring index, but no increased apnea index. The data suggest that cleft palate patients having undergone primary closure of the palate demonstrate microsymptoms of nocturnal upper airway obstruction.
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