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Influence of percutaneous endoscopic gastrostomy on gastroesophageal reflux: a prospective study in 68 children

Stefan Razeghi1, Thomas Lang, Rolf Behrens

  • 1Department of Pediatrics and Adolescent Medicine, Friedrich Alexander University of Erlangen, Germany. stefanrazeghi@yahoo.de

Journal of Pediatric Gastroenterology and Nutrition
|July 27, 2002
PubMed

Insights

Percutaneous endoscopic gastrostomy (PEG) generally does not cause gastroesophageal reflux (GER). However, PEG placement in the antrum may increase reflux, suggesting it could be unfavorable for patients.

Area of Science:

  • Gastroenterology
  • Endoscopy
  • Digestive Health

Background:

  • Gastroesophageal reflux (GER) is a potential complication of percutaneous endoscopic gastrostomy (PEG).
  • Existing research on PEG and GER presents conflicting findings.

Purpose of the Study:

  • To investigate the impact of percutaneous endoscopic gastrostomy (PEG) on gastroesophageal reflux (GER).
  • To determine if PEG placement influences the incidence or severity of GER.

Main Methods:

  • Prospective 24-hour pH monitoring in 68 patients before and after PEG placement.
  • Patients had no prior GER treatment.

Main Results:

  • No significant difference in abnormal pH monitoring results before and after PEG insertion (22.1% vs. 25%).
  • Median reflux index showed no significant change overall (2.6% vs. 3.4%).
  • Significant increase in median reflux index observed only in patients with antral PEG placement (1.8 to 5.4).

Conclusions:

  • Percutaneous endoscopic gastrostomy (PEG) is generally not associated with the development of gastroesophageal reflux (GER).
  • Antral placement of PEG may be unfavorable and potentially increase GER.
Abstract

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