Histiocytic medullary reticulosis (malignant histiocytosis) in Zambia

Fifteen cases of histiocytic medulary reticulosis are reported from Zambia, Africa. The importance of liver biopsy in the diagnosis is stressed. Forty cases have now been described from East and Central Africa suggesting a much higher incidence than in other parts of the world. It is thought that this may be due to prolonged stimulation of the reticuloendothelisl system.