Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Do seizures beget seizures?

W Allen Hauser1, Ju R Lee

  • 1Sergievsky Center, College of Physicians and Surgeons, Columbia University, 630 W 168 Street, New York, NY 10032, USA. wah1@spyral.net

Progress in Brain Research
|July 30, 2002
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reader Response: Seizures and Epilepsy in Association With Neurocysticercosis: a Nosologic Proposal.

Neurology·2026
Same author

Identification of abnormal patterns of evolution of neurocysticercosis cysts and what they might indicate.

medRxiv : the preprint server for health sciences·2025
Same author

Use of Antiseizure Medications Early in Pregnancy and the Risk of Major Malformations in the Newborn.

Neurology·2025
Same author

Impact of albendazole treatment on the symptom profile of neurocysticercosis patients 14-16 years following diagnosis.

Parasitology·2025
Same author

How patient, infection and cysticercus characteristics impact the evolution of <i>Taenia solium</i> larva in the human brain: A unique cyst-level analysis.

Parasitology·2025
Same author

Familial aggregation of seizure outcomes in four familial epilepsy cohorts.

Epilepsia·2024
Same journal

Preface.

Progress in brain research·2025
Same journal

Mindfulness and meditation: Promoting emotional and cognitive health.

Progress in brain research·2025
Same journal

Cognitive stimulation enhancing memory and mental function.

Progress in brain research·2025
Same journal

The science behind non-pharmacological interventions.

Progress in brain research·2025
Same journal

Technology-assisted interventions for neuropsychiatric disorders.

Progress in brain research·2025
Same journal

Ethical consideration in non-pharmacological treatments for neuropsychiatric disorders.

Progress in brain research·2025
See all related articles

Each seizure increases the risk of future seizures in individuals experiencing their first unprovoked seizure. This progressive increase in seizure risk with more seizures has been demonstrated in humans for the first time.

Area of Science:

  • Neurology
  • Neuroscience
  • Epileptology

Background:

  • Seizures may alter brain function, potentially increasing the risk of subsequent seizures.
  • Previous studies on seizure recurrence risk have been limited by inadequate study designs.

Purpose of the Study:

  • To evaluate the risk of seizure recurrence after a first unprovoked seizure.
  • To investigate the relationship between the number of seizures and the risk of future seizures.

Main Methods:

  • Analysis of a cohort identified at their first unprovoked seizure.
  • Assessment of seizure recurrence risk based on the number of prior seizures.

Main Results:

  • Individuals with an initially low risk for seizure recurrence showed a significant increase in risk as the number of seizures increased.

Related Experiment Videos

  • This study provides the first human evidence of a progressive increase in seizure risk with an increasing number of seizures.

    • Conclusions:

    • The findings demonstrate a dynamic relationship between seizure occurrence and future seizure risk in humans.
    • Competing mechanisms likely exist that both increase seizure susceptibility and promote seizure suppression.
    • Further research, including the development of appropriate animal models, is needed to elucidate these interacting processes.