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Related Experiment Videos

Pfiesteria complex organisms and human illness.

David N Collier1, William A Burke

  • 1Division of Dermatology, Brody School of Medicine at East Carolina University, Greenville, NC, USA.

Southern Medical Journal
|July 30, 2002
PubMed
Summary

Exposure to Pfiesteria piscicida and related Pfiesteria complex organisms (PCOs) can cause human illness, including cognitive impairment. Further research is needed to identify toxins and develop diagnostic tests for PCO-related health issues.

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Area of Science:

  • Marine Biology
  • Toxicology
  • Environmental Health

Background:

  • Pfiesteria piscicida and similar dinoflagellates are known as Pfiesteria complex organisms (PCOs).
  • Concerns exist regarding the potential health risks posed by PCOs.

Purpose of the Study:

  • To evaluate the human health threat from PCOs.
  • To address common misconceptions about these organisms.

Main Methods:

  • Literature review of P. piscicida and PCOs.
  • Databases searched include MEDLINE and Sea Grant.
  • Information also sourced from internet sites.

Main Results:

  • Laboratory exposure to P. piscicida aerosols caused reversible cognitive impairment and memory loss in researchers.

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  • Biologic, animal model, and epidemiologic studies support these findings.

    • Conclusions:

    • Human illness can result from exposure to P. piscicida and other PCOs.
    • Detecting PCO toxins and diagnosing related illnesses is challenging without further isolation and purification.