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Acute esophageal necrosis: a 1-year prospective study
Emmanuel Ben Soussan1, Guillaume Savoye, Patrick Hochain
1Digestive Tract Research Group and Department of Pathology, Rouen University Hospital, Rouen Cedex, France.
Acute esophageal necrosis, a condition causing a black esophagus, affects 0.2% of patients. This finding is linked to poor health and is not solely a local issue.
Area of Science:
- Gastroenterology
- Pathology
Background:
- Prospective study to evaluate acute esophageal necrosis (AEN) unrelated to caustic ingestion.
- Assessed frequency, clinical spectrum, histology, and follow-up of AEN.
Purpose of the Study:
- Determine the incidence and clinical characteristics of AEN.
- Understand the association of AEN with patient health status.
Main Methods:
- Endoscopic diagnosis (black esophagus) and histology confirmed AEN.
- Excluded caustic/corrosive ingestion.
- Recorded medical history, symptoms, and nutritional status.
- Treatment involved parenteral nutrition and proton pump inhibitors.
- Follow-up endoscopy assessed regression.
Main Results:
- Identified 8 cases (0.2%) of AEN among 3900 endoscopies.
- 6 patients had poor nutritional status.
- 4 patients showed complete resolution; no strictures developed.
- 4 deaths occurred, unrelated to AEN.
Conclusions:
- AEN is a more frequent finding than previously reported.
- AEN is associated with poor general health and systemic factors.
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