Related Experiment Videos
Cytologic appearance of pigmented villonodular synovitis. A case report
Sanjiv Gupta1, Ravi Shankar Mishra
1Department of Pathology, Cancer Hospital and Research Institute, Gwalior, M.R., India. sanjiv_1961@usa.net
Acta Cytologica
|July 31, 2002
Summary
Pigmented villonodular synovitis (PVNS), a joint neoplasm, can be diagnosed preoperatively. Fine needle aspiration cytology reveals characteristic cells, siderophages, and giant cells, aiding in diagnosis.
Area of Science:
- Orthopedic Pathology
- Cytopathology
- Neoplastic Diseases
Background:
- Pigmented villonodular synovitis (PVNS) is a benign neoplastic proliferation of the synovium.
- PVNS typically affects large joints and can exhibit locally aggressive behavior.
- Cytologic features of PVNS require further characterization for diagnostic accuracy.
Observation:
- A case study of a 70-year-old male with an ankle mass is presented.
- Histopathologic diagnosis confirmed pigmented villonodular synovitis.
- Cytologic examination of smears showed distinct cellular and extracellular components.
Findings:
- Cytologic smears revealed clusters of bland, round to ovoid cells.
- Siderophages, indicative of hemosiderin deposition, were present.
- Binucleated and multinucleated giant cells were observed, consistent with PVNS.
Implications:
- Fine needle aspiration cytology can provide a preoperative diagnosis of PVNS.
- Accurate preoperative diagnosis facilitates appropriate clinical management.
- Understanding cytologic features improves diagnostic yield in joint neoplasms.