Related Experiment Video

Updated: Sep 30, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
07:43

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas

Published on: January 17, 2018

[Open versus video-endoscopic approach in the treatment of hypercortisolism by bilateral adrenalectomy]

Y Chapuis1, B Dousset, J Pitre

  • 147 avenue du Maréchal Lyautey-75016 Paris.

Bulletin De L'Academie Nationale De Medecine
|July 31, 2002
PubMed

Insights

Bilateral video endoscopic adrenalectomy (BVA) offers improved postoperative outcomes compared to open surgery for hypercortisolism (HC). This minimally invasive approach leads to reduced pain, faster recovery, and fewer complications, making it a valuable alternative.

Area of Science:

  • Endocrinology
  • Surgical Oncology
  • Minimally Invasive Surgery

Background:

  • Bilateral adrenalectomy (BA) indications for hypercortisolism (HC) have decreased due to advancements in hypophysectomy and imaging.
  • BA remains crucial for refractory HC post-pituitary surgery, ACTH ectopic secretion, and autonomous adrenal secretion.

Purpose of the Study:

  • To evaluate the efficacy and safety of bilateral video endoscopic adrenalectomy (BVA) compared to traditional open adrenalectomy for HC treatment.

Main Methods:

  • A retrospective study comparing 88 patients undergoing open adrenalectomy (Group 1) over 20 years with 62 patients undergoing BVA (Group 2) since 1994.
  • Data analysis focused on preoperative complications, postoperative morbidity, pain, hospital discharge, and parietal complications.

Main Results:

  • Two deaths occurred in the open surgery group (Group 1).
  • Preoperative complication rates were similar between groups.
  • Postoperative morbidity was significantly lower in the BVA group (Group 2), with reduced pain, simpler follow-up, and faster hospital discharge.

Conclusions:

  • Bilateral video endoscopic adrenalectomy (BVA) demonstrates superior postoperative outcomes compared to open adrenalectomy.
  • BVA offers benefits such as decreased pain, simplified follow-up, and shorter hospital stays.
  • Successful BVA requires specialized surgeon training and an adaptation period.

More Related Videos

A Novel Method: Super-selective Adrenal Venous Sampling06:08

A Novel Method: Super-selective Adrenal Venous Sampling

Published on: September 15, 2017

Related Concept Videos

Cushing Syndrome I: Introduction01:26

Cushing Syndrome I: Introduction

Cushing syndrome refers to the collection of clinical manifestations that arise when tissues are exposed to excessive amounts of cortisol or cortisol-like medications over an extended period. Cortisol, a glucocorticoid produced by the adrenal cortex, regulates metabolism, immune responses, and the body’s adaptation to stress. When its concentration remains chronically elevated, these physiological pathways become dysregulated, resulting in the characteristic features of the syndrome.Exogenous...
Cushing Syndrome II: Pathophysiology01:19

Cushing Syndrome II: Pathophysiology

Cortisol production is normally governed by the hypothalamic–pituitary–adrenal (HPA) axis, which maintains hormonal balance through tightly regulated feedback mechanisms. Disruption of this regulatory system is central to the development of Cushing syndrome, whether the excess cortisol originates from external medications or internal pathology. Persistent cortisol elevation alters metabolism, immune function, and endocrine signaling, producing the characteristic clinical features of the...
Psychosurgery01:30

Psychosurgery

Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
Endoscopic Studies I: Bronchoscopy and Thoracoscopy01:30

Endoscopic Studies I: Bronchoscopy and Thoracoscopy

Endoscopy is a non-surgical medical technique used to examine a person's internal organs and vessels. This lesson will focus on two types of endoscopic studies: bronchoscopy and thoracoscopy.
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due to...