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Incidental findings in pelvic lymph nodes at radical prostatectomy
A M Winstanley1, A Sandison, S R J Bott
1Department of Histopathology, North Midllesex Hospital, UCL Hospitals NHS Trust, London WC1E 6JJ, UK.aliwinstanley@doctors.org.uk
Aims:
To assess the frequency and cause of incidental (non-metastatic) lymph node pathology discovered before or at radical prostatectomy.
Methods:
Eight hundred and fifty four consecutive lymphadenectomies received between 1988 and 2001 were reviewed. All had been processed and stained routinely. Additional techniques, indicated by morphology, were then performed.
Results:
Incidental pathology was found in 15 cases: florid sinus histiocytosis following prosthetic joint replacement (eight), non-caseating granulomas (three), small lymphocytic cell lymphoma (two), follicular lymphoma (one), and foreign body reaction (one). Incidental pathology was present in 1.8% of 854 patients who underwent pelvic lymphadenectomy during radical prostatectomy.
Conclusion:
Awareness of possible non-metastatic lymph node pathology aids histological diagnosis and may be clinically relevant.