Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Mitral valve surgery: when is it appropriate?

Vinay Badhwar1, Steve F Bolling

  • 1Section of Cardiac Surgery, University of Michigan, Ann Arbor, MI 8109-0344, USA.

Congestive Heart Failure (Greenwich, Conn.)
|July 31, 2002
PubMed
Summary

Mitral valve repair using flexible annuloplasty rings offers a safe and effective treatment for cardiomyopathy patients with severe mitral regurgitation. This approach improves heart function and survival rates, establishing it as a new management strategy.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Coronary Artery Bypass Grafting versus Percutaneous Coronary Intervention for Stable Multivessel Coronary Disease in the Current Era.

The Annals of thoracic surgery·2026
Same author

Five-Year Outcomes of Transcatheter Mitral Valve Replacement in Patients With Severe Symptomatic Mitral Regurgitation: Results From the Tendyne Expanded Clinical Study.

ESC heart failure·2026
Same author

Longitudinal Surgical Aortic Valve Replacement Outcomes for Asymptomatic Severe Aortic Stenosis With Preserved Ejection Fraction.

The Annals of thoracic surgery·2026
Same author

Current Incidence and Modality of Young Aortic Valve Replacement in the United States.

Circulation·2026
Same author

Convenience Now, Complexity Later: Transcatheter Aortic Valve Replacement in Young Patients.

The Annals of thoracic surgery·2026
Same author

Bioprosthetic versus mechanical surgical aortic valve replacement in patients ≥65 years of age.

JTCVS open·2026

Area of Science:

  • Cardiology
  • Cardiac Surgery
  • Heart Failure Management

Background:

  • Mitral regurgitation (MR) frequently complicates end-stage cardiomyopathy.
  • Traditional treatments (medical management, valve replacement) yield poor outcomes in these patients.

Purpose of the Study:

  • To evaluate the safety and efficacy of mitral valve reconstruction for severe MR in cardiomyopathy patients.
  • To assess long-term survival and functional improvements following mitral valve repair.

Main Methods:

  • Prospective study of 150 patients with severe MR and cardiomyopathy (low ejection fraction, NYHA class III/IV).
  • All patients underwent mitral valve repair using an undersized, flexible annuloplasty ring.
  • Follow-up included echocardiography, survival analysis, and functional assessments.

Related Experiment Videos

Main Results:

  • Low perioperative mortality (1 intraoperative, 7 within 30 days).
  • High rates of successful repair with no or trivial residual MR.
  • Improved New York Heart Association class (mean 3.2 to 1.8) and ejection fraction.
  • Favorable 1-, 2-, and 5-year survival rates (82%, 71%, 57%).

Conclusions:

  • Mitral valve repair with flexible annuloplasty is safe and effective for MR in cardiomyopathy.
  • The procedure promotes reverse remodeling and restores normal left ventricular geometry.
  • Mitral reconstruction represents a new first-line strategy for MR in end-stage heart failure.