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[Developmental disorders and schizophrenia].

Mario Speranza1, Nadia Younès

  • 1Centre hospitalier universitaire de psychiatrie de l'enfant et de l'adolescent Fondation Vallée CHU de Bicêtre 94275 Le Kremlin-Bicêtre. mariosperanza@wanadoo.fr

La Revue Du Praticien
|August 1, 2002
PubMed
Summary

Developmental disorders in childhood may indicate a risk for developing schizophrenia later in life. Early interventions show promise, but the exact role of these abnormalities requires further investigation.

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Area of Science:

  • Neuroscience
  • Developmental Psychology
  • Psychiatry

Context:

  • The link between developmental disorders and schizophrenia is a significant area of research.
  • Studies indicate motor, social, and cognitive abnormalities in the premorbid history of individuals with schizophrenia.

Purpose:

  • To explore the relationship between developmental abnormalities and schizophrenia.
  • To discuss the implications of neuro-developmental theories versus vulnerability models.
  • To consider the role of early interventions in managing these conditions.

Summary:

  • Developmental abnormalities, including motor, social, and cognitive deficits, are frequently observed in individuals who later develop schizophrenia.
  • Two primary theories explain these findings: the neuro-developmental theory suggests underlying cerebral lesions, while the vulnerability model posits them as risk factors.

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  • The therapeutic approach depends on understanding the nature of these abnormalities, with early interventions showing established benefits.

    • Impact:

    • Highlights the importance of early identification and intervention for developmental disorders that may be associated with schizophrenia risk.
    • Informs clinical practice regarding the management of individuals with a history of developmental abnormalities and potential schizophrenia.
    • Contributes to the ongoing debate on the etiology of schizophrenia, differentiating between precursor lesions and risk factors.