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[Keratoprostheses. Clinical aspects].

K Hille1

  • 1Universitäts-Augenklinik und Poliklinik, Kirrberger Strasse 1, 66421 Homburg/Saar. aukhil@uniklinik-saarland.de

Der Ophthalmologe : Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft
|August 1, 2002
PubMed
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Keratoprosthesis implantation offers visual restoration for severe corneal diseases. Osteo-odonto-keratoprostheses provide excellent long-term outcomes, while alternative materials suit patients without suitable teeth.

Area of Science:

  • Ophthalmology
  • Biomaterials Science

Context:

  • Severe corneal conditions like pemphigoid, Fuchs-Stevens-Johnson syndrome, and xerophthalmia often necessitate keratoprosthesis.
  • Corneal vascularization from burns, transplant rejection, or cloudy corneas in silicone-filled eyes are indications for prosthetic intervention.

Purpose:

  • To review the indications, outcomes, and complications associated with various keratoprosthesis types.
  • To highlight the long-term efficacy of osteo-odonto-keratoprostheses and alternatives like the Pintucci keratoprosthesis.

Summary:

  • Keratoprosthesis is crucial for visual acuity restoration in eyes with severe corneal pathology and vascularization.
  • While complications like glaucoma and prosthesis loss exist, osteo-odonto-keratoprostheses offer durable results, with biointegrable options available for toothless patients.

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  • Adequate management of pre-existing or secondary glaucoma is essential for successful outcomes.
  • Impact:

    • Keratoprosthesis surgery can significantly improve vision in patients with otherwise untreatable corneal blindness.
    • Advancements in keratoprosthetic materials, including biointegrable options, expand treatment possibilities.
    • Long-term monitoring and management of complications, particularly glaucoma, are critical for sustained visual function.