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Updated: Aug 19, 2026

Generation of a Chronic Obstructive Pulmonary Disease Model in Mice by Repeated Ozone Exposure
Published on: August 25, 2017
Chronic obstructive pulmonary disease. 1: Susceptibility factors for COPD the genotype-environment interaction
1University of British Columbia McDonald Research Laboratories/iCAPTURE Center, St Paul's Hospital, Vancouver, BC, Canada. asandford@mrl.ubc.ca
Abstract:
Genetic factors including alpha(1)-antitrypsin deficiency are important in COPD. Candidate gene association studies in COPD are reviewed. Efforts to identify interactions between genetic factors and environmental determinants such as smoking may lead to improved understanding of the pathogenesis of the disease.
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