[Cardiac tamponade as the first clinical manifestation of squamous cell carcinoma]
Related Experiment Videos
Jacek Orski1, Dorota Telesińska, Adam Curyło
1Katedra i Klinika Chorób Wewnetrznych, Gerontologii Collegium Medicum, Uniwersytetu Jagiellońskiego, 31-531 Kraków, ul. Sniadeckich 10.
Abstract:
The case concerns a 56 year old male with the diagnosis of squamous cell carcinoma, which clinically presented as a rapidly increasing cardiac tamponade. The patient underwent a pericardio-centesis. Due to the expansion of the process within the bronchus, the patient underwent chemotherapy according to the Taxol + Carboplatine scheme. After 8 months of treatment the patient was hospitalized again due to a further increase in fluid in the pericardium, and symptoms of cardiac insufficiency which lead to patient death. Autopsy revealed neoplastic change within the pericardium (fibrinous-hemorrhagic pericarditis and hemopericardium). Cardiac tumors occur rarely, they may be primary or secondary. Squamous cell carcinoma metastases may be the cause of pericardial effusion, which is associated with poor prognosis.
Related Concept Videos
Introduction Cardiac Emergencies
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Heart Failure III: Clinical Manifestations
Coronary Artery Disease III: Clinical Manifestations
Metastasis
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations