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Cyclization of 1,6-enynes with allylic chromate species
Toshihiro Nishikawa1, Hiroshi Shinokubo, Koichiro Oshima
1Department of Material Chemistry, Graduate School of Engineering, Kyoto University, Japan.
Organic Letters
|August 3, 2002
Abstract:
[reaction: see text] Treatment of 1,6-enynes with tetramethallylchromate induces a cyclization reaction with concurrent introduction of a methallyl group. A catalytic amount of CrCl(3) combined with methallylmagnesium chloride also achieves this cyclization process. The resultant cyclic organometallic species undergo further functionalization upon reaction with electrophiles.