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[Proceedings: Evaluation of the plasma-phenolred test as a simple kidney function test]
Schweizerische Medizinische Wochenschrift
|December 20, 1975
Summary
The phenolsulphthalein 60/60 plasma test (PSP 60/60) is a simple and effective screening tool for assessing kidney function. It outperforms serum creatinine and urea nitrogen tests in patients with chronic kidney disease.
Area of Science:
- Nephrology
- Clinical Chemistry
Context:
- Chronic renal disease impacts kidney function.
- Accurate assessment of renal insufficiency is crucial for patient management.
Purpose:
- To evaluate the phenolsulphthalein 60/60 plasma test (PSP 60/60) as a screening tool for renal function.
- To compare PSP 60/60 with serum creatinine and urea nitrogen levels.
- To assess the correlation of PSP 60/60 with established renal clearance measures.
Summary:
- The phenolsulphthalein 60/60 plasma test (PSP 60/60) was assessed in 30 controls and 60 patients with chronic renal disease.
- PSP 60/60 demonstrated superiority over serum creatinine and urea nitrogen, correlating well with endogenous creatinine and 131I-iodohippurate clearance in over 80% of cases.
- Drugs affecting renal excretory mechanisms were identified as key interfering factors.
Impact:
- PSP 60/60 offers a technically simple and valuable screening method for renal function assessment.
- Its utility is particularly noted as an office procedure for evaluating kidney health.
- This test aids in the early detection and management of renal insufficiency.