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Related Experiment Videos

Improved contrast to tissue ratio at higher harmonics.

Ayache Bouakaz1, Sigmund Frigstad, Folkert J Ten Cate

  • 1Experimental Echocardiography, Erasmus University Rotterdam, Thoraxcentre, The Netherlands. bouakaz@tch.fgg.eur.nl

Ultrasonics
|August 6, 2002
PubMed
Summary

This study enhances ultrasound contrast imaging by utilizing higher harmonic frequencies, significantly improving contrast-to-tissue ratio (CTR) for better tissue discrimination. A novel wideband transducer boosts CTR by 40 dB for super harmonic imaging.

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Area of Science:

  • Medical Imaging
  • Biomedical Ultrasound
  • Acoustics

Background:

  • Ultrasound contrast imaging aims to differentiate perfused tissue from contrast bubbles, quantified by contrast-to-tissue ratio (CTR).
  • Second harmonic imaging offers higher CTR than fundamental frequency imaging but is limited by nonlinear wave propagation and tissue harmonic scattering.
  • Reducing nonlinear distortion is key to increasing CTR in harmonic ultrasound imaging.

Purpose of the Study:

  • To investigate the relationship between harmonic number and CTR in ultrasound contrast imaging.
  • To develop and evaluate a novel wideband phased array transducer for super harmonic imaging.
  • To demonstrate significant CTR improvements using higher harmonic components.

Main Methods:

  • Utilized a new wide frequency band phased array transducer capable of transmitting at lower frequencies and detecting super harmonics (third, fourth, fifth, and ultraharmonics).

Related Experiment Videos

  • Performed in-vitro measurements to assess CTR improvements.
  • Validated findings with calculations based on existing models for encapsulated bubbles and nonlinear propagation theory.

    • Main Results:

    • Demonstrated that CTR increases with the harmonic number, particularly at lower transmission frequencies.
    • Achieved a substantial 40 dB increase in CTR for super harmonic components compared to conventional second harmonic imaging.
    • Observed results consistent with theoretical models for nonlinear ultrasound propagation and bubble response.

    Conclusions:

    • Higher harmonic imaging, especially super harmonics, significantly enhances CTR in ultrasound contrast imaging.
    • The developed wideband transducer effectively leverages super harmonics for superior contrast-tissue discrimination.
    • This advancement holds potential for improved diagnostic capabilities in ultrasound contrast imaging.