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Updated: Sep 30, 2026

A Microwave-Assisted Direct Heteroarylation of Ketones Using Transition Metal Catalysis
Published on: February 16, 2020
Routes to regioselective deuteriation of heteroaromatic compounds
Wesley R Browne1, Christine M O'Connor, J Scott Killeen
1National Centre for Sensor Research, School of Chemical Sciences, Dublin City University, Dublin 9, Ireland.
Abstract:
A systematic approach to the deuteriation of polypyridyl type ligands is reported. A range of isotopologues of heteroaromatic compounds containing pyrazyl, pyridyl, 1,2,4-triazole, thienyl, methyl, and phenyl moieties, have been prepared in a cost-effective manner, using a range of methods based on subcritical aqueous media. Selectively and fully deuteriated ligands are characterized by mass spectrometry and(1)H, (2)D, and (13)C NMR spectroscopy. The application of deuteriation to supramolecular chemistry is discussed.
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