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Related Experiment Videos

Low Cerebrospinal Fluid Pressure Headache.

Christine M. Lay1

  • 1The Headache Institute, St. Luke's-Roosevelt Hospital Center, 1000 Tenth Avenue, Suite 1C-10, New York, NY 10019, USA.

Current Treatment Options in Neurology
|August 7, 2002
PubMed
Summary
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Spontaneous intracranial hypotension (SIH) causes headaches and other symptoms due to low cerebrospinal fluid (CSF) pressure. Diagnosis involves imaging, and treatment often includes epidural blood patch or surgery for persistent CSF leaks.

Area of Science:

  • Neurology
  • Neurosurgery

Background:

  • Alterations in cerebrospinal fluid (CSF) pressure cause neurological symptoms, most commonly headache.
  • Spontaneous intracranial hypotension (SIH) is an increasingly recognized syndrome characterized by low CSF pressure and associated symptoms.

Purpose of the Study:

  • To describe the clinical presentation, diagnostic findings, and treatment options for spontaneous intracranial hypotension (SIH).

Main Methods:

  • Review of clinical presentation, diagnostic imaging (MRI, CT myelography, radiocisternography), and treatment outcomes for SIH patients.
  • Analysis of cerebrospinal fluid (CSF) pressure measurements and fluid analysis.

Main Results:

  • SIH typically presents with orthostatic headache, nausea, vomiting, and other neurological symptoms.

Related Experiment Videos

  • Imaging reveals diffuse pachymeningeal enhancement, brain sagging, and tonsilar descent.
  • Low CSF pressure is characteristic, though it may be normal in intermittent leaks.

    • Conclusions:

    • SIH is a distinct syndrome often caused by spontaneous CSF leaks.
    • Diagnosis is confirmed by characteristic imaging findings.
    • Epidural blood patch (EBP) is the primary treatment, with surgery reserved for refractory cases.