Investigation of QT-interval dispersion in the electrocardiogram of 81 dogs

S G Dennis1, N J Summerfield, A Boswood

  • 1Section of Cardiology, University of Pennsylvania, School of Veterinary Medicine, Philadelphia 19104-6010, USA.

The Veterinary Record
|August 8, 2002
PubMed

Insights

This study established normal QT interval dispersion (QT dispersion) ranges in dogs, finding no significant difference in dogs with cardiac disease. Further research is needed due to potential measurement errors.

Area of Science:

  • Veterinary Cardiology
  • Electrophysiology
  • Cardiac Diagnostics

Background:

  • QT interval dispersion (QT dispersion) indicates ventricular repolarization inhomogeneity.
  • Increased QT dispersion is linked to sudden death and arrhythmias in human cardiac diseases.
  • QT dispersion has not been evaluated in canine populations.

Purpose of the Study:

  • To establish a normal reference range for QT dispersion in dogs.
  • To assess the impact of cardiac disease on QT dispersion in dogs.

Main Methods:

  • Ten-lead electrocardiograms (ECGs) were recorded from 81 dogs across two veterinary hospitals.
  • Data from 68 dogs (32 normal, 36 with cardiac disease) were analyzed.
  • QT dispersion and heart rate-corrected QT dispersion were calculated.

Main Results:

  • The mean QT dispersion was 20.8 (18.2 ms).
  • The mean heart rate-corrected QT dispersion was 26.1 (23.6 ms).
  • No significant effect of cardiac disease on QT dispersion was observed.

Conclusions:

  • This study provides initial reference values for canine QT dispersion.
  • Cardiac disease did not significantly alter QT dispersion in this cohort.
  • Potential measurement errors necessitate cautious interpretation and further validation.

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