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A Modified Two Kidney One Clip Mouse Model of Renin Regulation in Renal Artery Stenosis
08:21

A Modified Two Kidney One Clip Mouse Model of Renin Regulation in Renal Artery Stenosis

Published on: October 26, 2020

Renal artery involvement in patients of coronary artery disease undergoing coronary angiography--a prospective study

P C Rath1, M K Agarwala, P K Dhar

  • 1Apollo Hospitals Hyderabad, Jubilee Hills, India.

The Journal of the Association of Physicians of India
|August 8, 2002
PubMed

Insights

This study found a low incidence of significant renal artery stenosis in patients undergoing coronary angiography. While no direct link was found, severe coronary artery disease patients may benefit from renal angiography.

Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology
  • Nephrology

Background:

  • Renal artery stenosis (RAS) is a significant vascular disease.
  • Coronary artery disease (CAD) and RAS often coexist.
  • Identifying RAS in CAD patients is crucial for management.

Purpose of the Study:

  • To determine the angiographic incidence of renal artery stenosis.
  • To explore the association between RAS and cardiovascular risk factors.
  • To assess the relationship between RAS and the severity of coronary artery disease.

Main Methods:

  • Prospective study of 1000 consecutive patients undergoing coronary angiography.
  • Selective renal arteriography performed post-coronary angiography.
  • Analysis of patient demographics and cardiovascular risk factors.

Main Results:

  • A total of 10.3% of patients had renal artery disease.
  • Significant renal artery stenosis (<50%) was found in 2.5% of patients.
  • No statistically significant association was found between RAS and common risk factors like diabetes, hypertension, or hypercholesterolemia.

Conclusions:

  • The prevalence of significant RAS was low, precluding statistical analysis of its association with CAD severity.
  • A trend suggested increased RAS prevalence in patients with severe CAD or multiple risk factors.
  • Consideration of renal angiography in specific high-risk CAD subsets is recommended.
Abstract

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