Protective role of Bacopa monniera on morphine-induced brain mitochondrial enzyme activity in rats

Alcoholic extract of Bacopa monniera was tested for its protective role on morphine-induced brain mitochondrial enzyme status in rats. The level of the brain mitochondrial enzymes was significantly lower in the morphine-treated group when compared with control animals. These enzymes were maintained at normal level when Bacopa extract was administered orally at a dose of 40 mg/kg, 2 h before the administration of morphine.