Related Experiment Video
Updated: Aug 7, 2026

Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice
Published on: January 12, 2017
Clinical dentin hypersensitivity: understanding the causes and prescribing a treatment
1Oral Medicine Clinic, University of the Pacific, School of Dentistry, San Francisco, CA 94115, USA. pjacobse@uop.edu
Dentin hypersensitivity, characterized by tooth pain from exposed dentinal tubules, can be treated by covering tubules, plugging them, or desensitizing nerves. Effective management strategies offer relief for this common dental issue.
Area of Science:
- Dentistry
- Oral Health
- Dental Physiology
Background:
- Dentin hypersensitivity is a prevalent condition causing transient tooth pain.
- It stems from exposed dentinal tubules, often due to gingival recession and cementum loss.
- Brännström's hydrodynamic theory is the leading explanation for hypersensitivity pain.
Purpose of the Study:
- To summarize the causes and treatment strategies for dentin hypersensitivity.
- To differentiate hypersensitivity from other causes of tooth sensitivity.
- To inform about available treatment options for patients.
Main Methods:
- Review of the clinical causes of dentin hypersensitivity.
- Explanation of Brännström's hydrodynamic theory.
- Outline of three principal treatment strategies.
Main Results:
- Exposed dentinal tubules are the primary clinical cause, excluding bleaching or pathology.
- Treatment involves covering tubules (grafts/restorations), plugging tubules, or nerve desensitization.
- Potassium nitrate is used for nerve desensitization.
Conclusions:
- Dentin hypersensitivity requires accurate diagnosis before treatment.
- Multiple therapeutic approaches exist, including covering, plugging, and desensitizing tubules.
- Over-the-counter products are available for managing dentin hypersensitivity.
Related Concept Videos
Desensitization and Tachyphylaxis
Several...
Local Anesthetics: Differential Sensitivity of Nerve Fibers
Analgesia and Pain Management
Hypersensitivities
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Teeth
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...
Tooth Anatomy
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or grinding food.

