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Lipase Catalyzed Biosynthesis of Lactones
Bing-Feng Pan1, Jin-Wang Xu, Zu-Yi Li
1Shanghai Institute of Organic Chemistry, the Chinese Academy of Sciences, Shanghai 200032, China.
Abstract:
Lactones derived from hydroxy fatty acids have many applications. Compared to conventional chemical synthesis, lipases catalyzed synthesis of lactones is simple, mild and highly productive. The effects of hydroxy fatty acid chain length, solvents, lipase type and steric factor on the yield and on the distribution of the produced lactones were investigated.