Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Analysis and classification of cerebellar malformations.

Sandeep Patel1, A James Barkovich

  • 1Neuroradiology Section, University of California, San Francisco, San Francisco, CA 94143, USA.

AJNR. American Journal of Neuroradiology
|August 10, 2002
PubMed
Summary

This study proposes a new classification for cerebellar malformations, aiding in understanding their relationships. The system helps differentiate various types, including those with and without cerebral abnormalities.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

MRI, Child Opportunity Index, and 4-year cognitive outcome after neonatal encephalopathy.

Developmental medicine and child neurology·2026
Same author

Cumulative caffeine exposure predicts neurodevelopmental outcomes in premature infants.

Pediatric research·2025
Same author

Clinico-epidemiological Characteristics and Long-term Surgical Outcomes in Patients with Glomus Tumor: A Retrospective Study.

Indian dermatology online journal·2025
Same author

Feasibility Randomized Controlled Trial of Remotely Supervised Exercise versus Self-Directed Exercise for Intermittent Claudication.

Annals of vascular surgery·2025
Same author

Talar Malunion and Non-Union.

Foot and ankle clinics·2025
Same author

Fibular-Sided Avulsion of Posterior Inferior Tibiofibular Ligament-Patel-Sharma Fragment: A Case Report.

JBJS case connector·2025

Area of Science:

  • Neuroimaging
  • Developmental Neuroscience
  • Radiology

Background:

  • Cerebellar malformations are increasingly identified due to advanced MR imaging.
  • A need exists for a structured classification system for these conditions.

Purpose of the Study:

  • To describe and propose a rational classification for cerebellar malformations.
  • To aid in the segregation and understanding of relationships among cerebellar malformations.

Main Methods:

  • Retrospective review of MR images from 70 patients with cerebellar malformations.
  • Classification based on hypoplasia vs. dysplasia, focal vs. diffuse patterns, and brain stem/cerebral involvement.

Main Results:

  • Diffuse cerebellar dysplasia correlated with cerebral abnormalities in conditions like muscular dystrophy and lissencephaly.

Related Experiment Videos

  • Focal cerebellar dysplasia types (Joubert, rhombencephalosynapsis) showed variable cerebral involvement.
  • Nonsyndromic focal dysplasia and cerebellar hypoplasia generally presented with normal cerebra.
  • Dandy-Walker malformation exhibited both cerebellar hypoplasia and dysplasia, suggesting heterogeneity.

    • Conclusions:

    • The proposed classification facilitates understanding of cerebellar malformations.
    • This system is a foundational step towards integrating imaging and molecular biology for studying cerebellar development and maldevelopment.