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Visualizing Antigen Specific CD4+ T Cells using MHC Class II Tetramers
15:42

Visualizing Antigen Specific CD4+ T Cells using MHC Class II Tetramers

Published on: March 6, 2009

Defining antigen-specific responses with human MHC class II tetramers

Jane H Buckner1, Ursula Holzer, Erik J Novak

  • 1Benaroya Research Institute, Virginia Mason Research Center, 1201 Ninth Avenue, Seattle, WA 98101-2795, USA.

The Journal of Allergy and Clinical Immunology
|August 10, 2002
PubMed
Summary

HLA class II tetramers enable direct detection of antigen-specific CD4(+) T cells. These cells are crucial in immune responses, and tetramers offer new tools for clinical immunology and monitoring immunotherapy effectiveness.

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