[Acalculous acute cholecystitis during the course of typhoid fever in children]

J G Jaramillo Samaniego1

  • 1Cirujano Pediatra del Instituto de Salud del Niño.

Insights

Acalculous acute cholecystitis is a rare complication of typhoid fever in children. Surgical intervention is often necessary to prevent complications, though medical management with ultrasonography follow-up is an alternative for some patients.

Area of Science:

  • Pediatric Surgery
  • Infectious Diseases
  • Gastroenterology

Background:

  • Acalculous acute cholecystitis is an uncommon condition in pediatric patients.
  • It is a rare complication that can occur during the course of typhoid fever.

Purpose of the Study:

  • To determine the appropriate treatment strategies for acalculous acute cholecystitis in children with typhoid fever.
  • To evaluate the outcomes of surgical versus non-surgical management.

Main Methods:

  • A retrospective study was conducted on 10 pediatric patients diagnosed with acalculous cholecystitis during typhoid fever.
  • Data were collected from June 1992 to May 1997.

Main Results:

  • The study included 10 children (6 male, 4 female) aged 2.5 to 15 years.
  • Cholecystitis symptoms typically appeared within the first weeks of typhoid fever.
  • Treatment involved cholecystostomy (4 patients), cholecystectomy (3 patients), or medical management with ultrasonography (2 patients).
  • All patients received a 14-day course of chloramphenicol.
  • Post-operative complications included intestinal obstruction and intra-abdominal abscess in one patient each.

Conclusions:

  • Surgical intervention is generally recommended for acalculous acute cholecystitis in children with typhoid fever due to risks of gallbladder perforation and potential for becoming healthy carriers.
  • For patients unable to undergo surgery, medical treatment and ultrasonographic monitoring are advised.
Abstract

Related Concept Videos

Cholecystitis01:20

Cholecystitis

Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...
Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Cholera01:25

Cholera

Cholera is an acute gastrointestinal disease caused by the Gram-negative bacterium Vibrio cholerae. It is transmitted primarily via the fecal-oral route through the ingestion of contaminated water or food.Vibrio cholerae is a motile, Gram-negative bacterium of the family Vibrionaceae, primarily associated with waterborne outbreaks in areas with inadequate sanitation. Although over 200 serogroups of V. cholerae exist, only O1 and O139 are responsible for epidemic cholera. The O1 serogroup,...
Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
Acute Pharyngitis01:30

Acute Pharyngitis

Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause:
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...