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Updated: Sep 30, 2026

ALS - Motor Neuron Disease: Mechanism and Development of New Therapies
Published on: July 29, 2007
ALS, motor neuron disease, and related disorders: a personal approach to diagnosis and management
1Department of Neurology, Indiana University School of Medicine, Indianapolis, Indiana 46202-2859, USA.
Abstract:
Motor neuron disease, from diagnostic criteria, laboratory evaluation, communication with patients and their families, and the approach to long-term management represents a daunting challenge for many neurologists. Contained herein is a selective and biased discussion of several common dilemmas and questions that reflect recurring themes in the evaluation and management of patients with suspected motor neuron disease. The answers to these questions represent the author's opinions and are colored by personal experience, pearls graciously given to me by other experts in the field, and selected studies from the neuromuscular literature.
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