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Published on: October 30, 2010

Soft tissue amyloidoma with features of plasmacytoma: a case report and review

Hong Yin1, Nasir Alhasan, Alfonso Ciervo

  • 1Department of Pathology, Monmouth Medical Center, Long Branch, NJ 07740, USA.

Archives of Pathology & Laboratory Medicine
|August 13, 2002
PubMed

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Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
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