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Bi-lateral eosinophilic ulcers in an infant treated with propolis
A Kiderman1, R Torten, A L Furst
1Division of Family Medicine, The Hebrew University-Hadassah Medical School, Jerusalem, Israel.
The Journal of Dermatological Treatment
|August 13, 2002
Summary
Propolis ointment rapidly resolved chronic eosinophilic mouth ulcers in an infant. This natural bee product showed significant therapeutic potential for oral ulceration, warranting further investigation.
Area of Science:
- Oral Medicine
- Natural Products Research
- Pediatric Dermatology
Background:
- Propolis, a bee-derived substance rich in amino acids, flavonoids, terpenes, and cinnamic acid, has traditional uses for topical inflammatory conditions.
- Historically, propolis has been employed in folk medicine for treating various ulcerative lesions.
Observation:
- A 13-month-old female infant presented with bilateral eosinophilic ulcers of the mouth, the youngest reported case.
- Despite a 4-month course of various treatments, the oral ulcers remained unresponsive.
Findings:
- Local application of a lanolin-based propolis ointment led to rapid resolution of the ulcers within 3 weeks.
- The treated eosinophilic ulcers did not recur following the propolis ointment intervention.
Implications:
- The case suggests propolis may be a viable treatment for chronic eosinophilic ulcers in children.
- Further research into propolis for oral ulceration and other mucosal lesions is warranted due to its therapeutic potential.