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Iodopovidone pleurodesis for recurrent pleural effusions
Carlos A Olivares-Torres1, Rafael Laniado-Laborín, Cesáreo Chávez-García
1Department of Surgery, Hospital General de Tijuana, Tijuana, Mexico.
Chest
|August 13, 2002
Summary
Iodopovidone is an effective and safe agent for chemical pleurodesis in patients with recurrent pleural effusions. This study found a 96.1% success rate, making it a viable treatment option.
Area of Science:
- Pulmonology
- Thoracic Surgery
- Oncology
Background:
- Recurrent pleural effusions often require chemical pleurodesis when underlying causes are uncorrectable.
- The search for an ideal sclerosing agent for pleurodesis is ongoing.
- Iodopovidone is a potential candidate for pleurodesis due to its availability and low cost.
Purpose of the Study:
- To evaluate the efficacy and safety of iodopovidone for chemical pleurodesis.
- To assess the success rate of iodopovidone in managing recurrent pleural effusions.
Main Methods:
- A multicenter prospective study included 52 patients with recurrent pleural effusions.
- The pleurodesis solution comprised 10% iodopovidone mixed with normal saline.
- Procedures were performed via tube thoracostomy or at the end of diagnostic thoracoscopy.
Main Results:
- A complete response was achieved in 96.1% of patients (50 out of 52).
- Three patients (5.8%) experienced transient adverse effects (pain, hypotension).
- The mean follow-up was 13 months, with no 30-day postoperative deaths.
Conclusions:
- Iodopovidone is an effective and safe agent for chemical pleurodesis.
- It is a readily available and inexpensive alternative for managing incapacitating pleural effusions.
- The efficacy of iodopovidone is independent of the effusion etiology.