Anti-tumour necrosis factor therapy in Crohn's disease: where are we now?

A phase II dose ranging, double-blind, placebo-controlled study of alicaforsen enema in subjects with acute exacerbation of mild to moderate left-sided ulcerative colitis.

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A dose escalating, placebo controlled, double blind, single dose and multidose, safety and tolerability study of fontolizumab, a humanised anti-interferon gamma antibody, in patients with moderate to severe Crohn's disease.

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Abrogation of IFN-gamma mediated epithelial barrier disruption by serine protease inhibition.

Clinical and experimental immunology·2005

Lipopolysaccharide is transferred from high-density to low-density lipoproteins by lipopolysaccharide-binding protein and phospholipid transfer protein.

Infection and immunity·2005

Report on the Dutch consensus development meeting for implementation and further development of population screening for colorectal cancer based on FOBT.

Cellular oncology : the official journal of the International Society for Cellular Oncology·2005

A randomised, controlled, double blind, escalating dose study of alicaforsen enema in active ulcerative colitis.

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Expert consensus on clinical trials for use of systemic therapy in patients with hepatocellular carcinoma undergoing surgical and locoregional therapies.

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Butyrylcholinesterase alleviates hepatic stellate cell activation via paracrine muscarinic signalling.

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Prior endoscopic surveillance and diagnosis of Barrett-related dysplasia and cancer: evidence from a nationwide Dutch cohort.

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Current neuropharmacology·2026

Establishment of an in vitro human blood-brain barrier model for antiviral screening against neurotropic viruses.

Fluids and barriers of the CNS·2026

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International review of neurobiology·2026

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Related Experiment Videos

Anti-tumour necrosis factor therapy in Crohn's disease: where are we now?

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A phase II dose ranging, double-blind, placebo-controlled study of alicaforsen enema in subjects with acute exacerbation of mild to moderate left-sided ulcerative colitis.

A dose escalating, placebo controlled, double blind, single dose and multidose, safety and tolerability study of fontolizumab, a humanised anti-interferon gamma antibody, in patients with moderate to severe Crohn's disease.

Abrogation of IFN-gamma mediated epithelial barrier disruption by serine protease inhibition.

Lipopolysaccharide is transferred from high-density to low-density lipoproteins by lipopolysaccharide-binding protein and phospholipid transfer protein.

Report on the Dutch consensus development meeting for implementation and further development of population screening for colorectal cancer based on FOBT.

A randomised, controlled, double blind, escalating dose study of alicaforsen enema in active ulcerative colitis.

Expert consensus on clinical trials for use of systemic therapy in patients with hepatocellular carcinoma undergoing surgical and locoregional therapies.

Metastatic pancreatic cancer: from human disease to preclinical modelling.

Butyrylcholinesterase alleviates hepatic stellate cell activation via paracrine muscarinic signalling.

Integrative multi-omics landscape and diagnostic-therapeutic modelling of steatohepatitic hepatocellular carcinoma.

Hospitalisation in cirrhosis is linked to distinct gut microbiome structural and functional profiles: a multinational metagenomic study.

Prior endoscopic surveillance and diagnosis of Barrett-related dysplasia and cancer: evidence from a nationwide Dutch cohort.

Crosstalk and Convergence in Alzheimer's Disease: Integrating Brain Injury, Neuroinflammation, and Precision Medicine for Next-Generation Therapeutics.

Establishment of an in vitro human blood-brain barrier model for antiviral screening against neurotropic viruses.

The link between plasma and cognitive markers for Alzheimer's disease in Down syndrome: a longitudinal study.

The clinical utility of blood-based biomarkers of Alzheimer's disease: Triumphs and pitfalls.

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Anti-tumour necrosis factor therapy in Crohn's disease: where are we now?

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