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A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma
Published on: September 30, 2021
[Fibrolamellar hepatocarcinoma. Case report]
C Luque Vásquez1, I Chávez, R Caycho
1Cirujano Oncologo, Departamento de Cirugia, Hospital IV Alberto Sabogal, Essalud.
Abstract:
We reported a case with the hystologic diagnosis of fibromellar carcinoma. A 50 year-old woman without known risk factors for hepatocellular carcinoma. She appeared at the hospital with pain in the upper right quadrant, hepatomeglia and weight loss. The automated enhanced tomography evidenced a heterogeneous tumor with a diameter of 15 cm. compromising segments 4, 5, 6, 7 and 8 of the liver. Tumor calcifications and the retraction of the hepatic capsule were identified. Alpha-fetoprotein levels were normal and a negative serology for viral hepatitis were found. The patient underwent a surgical resection (extended right hepatectomy, the partial resection of the main biliary tract and a portal lymphadenectomy). Six months later she is asymptomatic and evidences no recurrence of the disease. The clinical, pathological, radiological features, treatment options and prognoses of fibrolamellar carcinoma were discussed.
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