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[Regulation of sugar content in the blood during artificial hyperglycaemia in chick embryos]
Zhurnal Evoliutsionnoi Biokhimii I Fiziologii
|September 1, 1975
Insights
Even 9-day chick embryos can regulate blood glucose levels after injections. This glucose regulatory system
Area of Science:
- Physiology
- Developmental Biology
Context:
- Investigating the development of glucose homeostasis in avian species.
- Examining the physiological response to glucose loading across different life stages.
Purpose:
- To determine the onset and developmental trajectory of the glucose regulatory system in chickens.
- To assess the capacity of embryos and chicks to maintain blood glucose stability.
Summary:
- Intravenous glucose injections were administered to 9-18 day chick embryos, 1-day chicks, and adult hens.
- Blood glucose levels were monitored at various time points post-injection (15 min to 8 hours).
- Results indicate that a glucose regulatory system is present by embryonic day 9, with increasing efficiency during development.
Impact:
- Provides foundational data for understanding avian glucose metabolism.
- Contributes to theoretical models of blood sugar regulation.
- Highlights the early development of homeostatic mechanisms in vertebrates.
Abstract:
Intravenous injections of glucose (8.6 mg/ml of blood) have been made 9-18 day chick embryos, 1-day chicks and adult hens. Glucose content of the blood was measured 15 and 30 min., 1,4 and 8 hours after the injection. It was shown that already 9-day embryos possess a regulatory system which restores the initial glycaemic level. During the development of the organism, the efficiency of this system increases. The data obtained may be used in theoretical studies on the sugar system of the blood.