Related Experiment Video
Updated: Jul 11, 2026

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
Published on: October 17, 2013
Colorectal cancer screening issues: a role for CT colonography?
1Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA.
Colorectal cancer screening compliance is low. Computed tomographic (CT) colonography shows promise as a more accessible screening tool, potentially improving patient adherence and reducing cancer deaths.
Area of Science:
- Oncology
- Radiology
- Public Health
Background:
- Colorectal cancer is a leading cause of cancer death in the US.
- Current screening methods have limitations in accessibility and patient compliance.
- Despite available tests, mortality rates remain high due to poor adherence.
Purpose of the Study:
- To review the natural history, risk factors, and prevention of colorectal cancer.
- To evaluate the strengths, limitations, and cost-effectiveness of current screening tests.
- To explore the potential of computed tomographic (CT) colonography as a novel screening tool.
Main Methods:
- Review of existing literature on colorectal cancer screening.
- Analysis of the characteristics of computed tomographic (CT) colonography.
- Discussion of factors influencing patient compliance with screening guidelines.
Main Results:
- Computed tomographic (CT) colonography offers advantages such as widespread scanner availability.
- It may overcome patient reluctance associated with other screening procedures like colonoscopy.
- Virtual bowel cleansing could enhance patient compliance.
Conclusions:
- Computed tomographic (CT) colonography presents a promising, albeit unproven, alternative for colorectal cancer screening.
- Increased patient compliance through improved screening methods like CT colonography could reduce mortality.
- Further development and validation are needed for widespread implementation.
Related Concept Videos
Radiological Investigation I: X-ray and CT
Assessment of the Rectum and Anus
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Imaging Studies I: CT and MRI
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Imaging Studies III: Gastrointestinal Motility Studies and Virtual Colonoscopy
Radionuclide Testing
Radionuclide testing is a sophisticated medical technique for assessing gastrointestinal motility. It focuses on gastric emptying and colonic transit time. Radioactive markers track the movement of food through the digestive system, providing insights into gastrointestinal disorders.
In gastric emptying studies, a meal's liquid and solid...
Endoscopic Procedures II: Colonoscopy
Imaging Studies III: Computed Tomography

