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Updated: Sep 30, 2026

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In Vitro ELISA Test to Evaluate Rabies Vaccine Potency
Published on: May 11, 2020
[Effect of tumor necrosis factor alpha on the efficiency of anti-rabies vaccination]
Voprosy Virusologii
|August 14, 2002
Abstract:
Recombinant tumor necrosis factor-alpha (TNF-alpha) improved the survival of random-bred albino mice vaccinated with antirabies vaccine after infection with rabies CVS strain. The agent dose of 0.1 microgram/animal, injected 1 day postvaccination, was the most effective. Improvement of antiviral resistance of non-vaccinated mice under the effect of TNF-alpha suggests that the effect of this factor on nonspecific resistance factors is one of the probable mechanisms of its modulating effect.

