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Updated: Sep 30, 2026

Production of E. coli-expressed Self-Assembling Protein Nanoparticles for Vaccines Requiring Trimeric Epitope Presentation
Published on: August 21, 2019
[Anti-HIV vaccines: state of the art and prospects]
Abstract:
The results of clinical trials of three types of candidate anti-AIDS vaccines are presented. Immunogenicity of different vaccine types and modern requirements to vaccines are analyzed. The advantages and disadvantages of protein, vector, and DNA vaccines and various protocols of vaccination are discussed and the advantages of the priming-booster immunization protocol are emphasized. Information about phase III clinical trials are presented. Tentative terms of introduction of vaccines into practice are presented.
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