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Updated: Sep 30, 2026

A Multilayer Microfluidic Platform for the Conduction of Prolonged Cell-Free Gene Expression
Published on: October 6, 2019
[Construction of an artificial digenic network with epigenetic properties]
T S Tropynina1, O V Golubev, E E Stupak
1Institute of Biology, Ufa Research Center, Russian Academy of Sciences, Ufa, 450054 Russia.
Abstract:
A model of the simplest epigene was constructed to have two alternative states, which proved to be stable and transmittable through Escherichia coli cell generations. A switch from one to another state was induced by thermal and chemical external signals. The results gave further insight into the dynamic mechanism of preservation, coding, and transmission of the genetic information.
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