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Cystic fibrosis in North Indian children

Meenu Singh1, Rajendra Prasad, Lata Kumar

  • 1Department of Pediatrics, Post Graduate Institute of Medical Education and Research, Chandigarh, India. meenusingh4@rediffmail.com

Indian Journal of Pediatrics
|August 14, 2002
PubMed

Insights

Cystic fibrosis (CF), a life-threatening inherited disorder, is increasingly reported in North India. This study details the diagnosis and management of pediatric CF cases at a leading medical institute.

Area of Science:

  • Genetics and наследственные заболевания
  • Pediatric medicine
  • Clinical research

Background:

  • Cystic fibrosis (CF) is the most prevalent lethal inherited disorder among Caucasians.
  • Over 900 CF mutations have been identified since the gene's discovery in 1989.
  • There is a notable increase in CF diagnoses in North India.

Purpose of the Study:

  • To present the experience of diagnosing and managing pediatric cystic fibrosis patients.
  • To highlight the growing incidence of CF in North India.
  • To share clinical insights from a tertiary care center.

Main Methods:

  • Retrospective review of pediatric patients diagnosed with cystic fibrosis.
  • Analysis of diagnostic procedures and treatment protocols employed.
  • Case series from Post-Graduate Institute of Medical Education and Research, Chandigarh.

Main Results:

  • The study details the clinical presentation and management strategies for pediatric CF.
  • Highlights challenges and successes in diagnosing and treating CF in the North Indian population.
  • Provides data on the frequency and characteristics of CF in the region.

Conclusions:

  • Cystic fibrosis diagnosis and management in North India require tailored approaches.
  • Increased awareness and early diagnosis are crucial for improving outcomes.
  • The experience at PGIMER, Chandigarh, offers valuable insights for regional healthcare providers.

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